[特邀报告]Assessing Tumor Microenvironment Immune Type with FDG-PET/CT - 报告详情

Assessing Tumor Microenvironment Immune Type with FDG-PET/CT
编号:37 访问权限:仅限参会人 更新:2021-11-02 17:31:06 浏览:140次 特邀报告

报告开始:2021年11月13日 14:45 (Asia/Shanghai)

报告时间:25min

所在会议:[PS1] Plenary Session 1 [NM1] Workshop on NM Session 1

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摘要
Recently, immune checkpoint inhibitors targeting the programmed death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis have become standard of care for patients with advanced non-small cell lung cancer (NSCLC). Tumor immune microenvironment could be classified into four types according to the status of PDL1 expression and CD8+ TIL abundance, while the tumors with tumor microenvironment immune type I (TMIT-I), i.e. with high PD-L1 expression and presence of CD8+ TILs, are more likely to benefit from anti-PD-L1/PD-1 therapies. FDG PET monitors the metabolism of glucose that is actively entrapped as nutrients in neoplastic tissues and tumor-associated activated immune cells. Therefore, FDG PET signals depicting the glucose metabolism are closely related to the characteristics of tumor immune microenvironment. We investigated the correlations between the metabolic parameters (MPs) of dual-time-point FDG PET images and the TMITs in patients with NSCLC, then strived to improve the ability of predicting TMIT-I through FDG PET/CT-based radiomics.
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报告人
Xiaohua Zhu
Professor Tongji Hospital, Huazhong University of Science and Technology

Tongji Hospital, Huazhong University of Science and Technology
Chair of Department of Nuclear Medicine
President of Nuclear Medicine Branch of Wuhan Medical Society
Standing Committee member of Nuclear Medicine Branch of Chinese Nuclear Society
Committee member of Nuclear Medicine Branch of Chinese Medical Doctor Association
Fellow of American College of Nuclear Medicine (FACNM)

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重要日期

摘要提交日期:

2021/08/31

2021/10/25

全文投稿日期:  

2021/09/15

2021/10/25

录取通知日期: 

2021/09/30

2021/11/01

会议日期:   2021-11-12-2021-11-14

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