Analysis of clinical and CT features of metastatic adenocarcinoma of the jaw
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Submission ID：41 View Protection：ATTENDEE
Updated Time：2021-10-30 07:00:08 Hits：905
Oral Presentation
Start Time：2021-11-13 15:30 （Asia/Shanghai）
Duration：15min
Session：[PS1] Plenary Session 1 » [OR1] Workshop on Oral Radiology
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Abstract
Objectives: To explore the clinical and computed tomography (CT) features of metastatic adenocarcinoma of the jaw (MAJ) with oral and maxillofacial lesions as the first symptom.
Methods: Fourteen cases of MAJ from 2006 to 2020 were collected, and clinical and CT features were analysed retrospectively.
Results: The primary sites were the lung (n = 6), liver (n = 4), kidney (n = 2), prostate (n = 1) and gastric cardia (n = 1). A radiological classification scheme of five types was tentatively proposed to discuss the complex CT features. Five cases were classified as osteolytic type with a permeative margin (100%, P < 0.05), and three were classified as mixed type, mostly with a moth-eaten margin (80%, P < 0.05). Cystic (n = 3) and alveolar bone resorption (n = 1) types had geographic margins, and osteoblastic-type (n = 1) had sclerotic margins. Moreover, nine cases showed periosteal reaction and five showed localised soft tissue mass, while the occurrence of jaw expansion was relatively rare.
Conclusions: MAJ is predominant in middle-aged and elderly men, and the most common site is the posterior mandible. This is the first time that a cystic and alveolar bone resorption type are proposed tentatively based on the jawbone structure. MAJ is characterised by numb chin syndrome (SCN), as well as a rapidly progressive osteolytic bone destruction with periosteal reaction and localised soft tissue mass, usually without jaw expansion on CT, which provides a basis for the clinical diagnosis of MAJ in the future.
Methods: Fourteen cases of MAJ from 2006 to 2020 were collected, and clinical and CT features were analysed retrospectively.
Results: The primary sites were the lung (n = 6), liver (n = 4), kidney (n = 2), prostate (n = 1) and gastric cardia (n = 1). A radiological classification scheme of five types was tentatively proposed to discuss the complex CT features. Five cases were classified as osteolytic type with a permeative margin (100%, P < 0.05), and three were classified as mixed type, mostly with a moth-eaten margin (80%, P < 0.05). Cystic (n = 3) and alveolar bone resorption (n = 1) types had geographic margins, and osteoblastic-type (n = 1) had sclerotic margins. Moreover, nine cases showed periosteal reaction and five showed localised soft tissue mass, while the occurrence of jaw expansion was relatively rare.
Conclusions: MAJ is predominant in middle-aged and elderly men, and the most common site is the posterior mandible. This is the first time that a cystic and alveolar bone resorption type are proposed tentatively based on the jawbone structure. MAJ is characterised by numb chin syndrome (SCN), as well as a rapidly progressive osteolytic bone destruction with periosteal reaction and localised soft tissue mass, usually without jaw expansion on CT, which provides a basis for the clinical diagnosis of MAJ in the future.
Keywords
Metastasis, Adenocarcinoma, Jawbone, Characteristic feature, Computed tomography
Speaker
姗 单
研究生 18361278383Submission Author
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Important Dates
| Abstract submission date: |
2021-10-25 |
| Full paper submission date: |
2021-10-25 |
| Notification of acceptance date: |
2021-11-01 |
| Conference date: | 2021-11-12~2021-11-14 |
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